Colloidal Silver has been used since the late 1800's in countless applications, and encompasses a wide variety of silver products. Many contain (claimed or unclaimed) salts, proteins, compounds or stabilizers, all of which affect the safety and efficacy of silver. Bio-active silver hydrosol represents the ultimate refinement of the colloidal silver category. It contains 98% positively charged silver, in pharmaceutical-grade purified water. Our unique silver species, with a verified and unmatched particle size, remains in its most active state for use within the body. Keep the following in mind when selecting a silver product, so you choose on that is safe and effective: 1. The EPA has an established daily reference dose (RFD) for silver of 350 micrograms of silver Many brands don't readily share this information because they know that their products far exceed this amount by upwards of 400% in one dose. It is safe to take 1 tsp of Sovereign silver 7x/day for 70 years and still be within the EPA RFD. However, you can only take 1/4 tsp (of the 1 tsp daily dose) of a competitor's 250 ppm product before you reach the RFD. Less is certainly more in this case. 2. Active concentration matters, not total concentration: Small particle size yields greater surface area, which through oxidation creates more positively charged silver. The larger the particle, the greater the amount of waste that your body must figure out how to excrete. It's this excess silver that can be toxic and potentially cause side effect such as Argyria, a benign condition that turns the skin blue. Think of it like trying to get rocks through an hourglass compared to sand. Sovereign Silver's unprecedented small particle size makes it easy for the body to absorb and excrete. Natural Immunogenic is an NSF certified GMP (Good Manufacturing Process) manufacturer.